HIV Drugs: Trigger of Autoimmunity

HIV Drugs: Trigger of Autoimmunity

Potentially severe hypersensitivity reactions to the anti-HIV drug abacavir occur through an autoimmune mechanism, resulting from the creation of drug-induced immunogens that are attacked by the body's immune system as all HIV Drugs blocks enzymes and protein synthesis which cause alteration in proteins and enzyme synthesis and autoimmune deformities accrue in HIV Patient.Many times Unexplained arthralgias and myalgias occur in about 5% of patients with HIV, sometimes in association with HIV seroconversion. HIV-associated arthralgia rarely progresses to inflammatory joint disease and is treated symptomatically.

  • Drug-Induced Autoimmunity
  • HIV and autoimmunity
  • Integrase Inhibitors, fusion Inhibitors and Entry Inhibitors
  • Immune Dysfunction & Antiretroviral Therapy
  • Reactions of HIV drug have autoimmune cause

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